生命科学コースでは「生命機能の解明」や「生物資源の開発」に興味を持つ意欲あふれる学生を募集しています。

研究力の生命科学コース

　

　　　　　

生命科学コースでは、動物、植物、微生物など多様な生物種を用いた様々な研究（卒業論文や修士?博士論文研究等）に学生?教員が日々取り組んでいます（各教員の専門分野についてはこちら）。これまでも大学ホームページなどで研究成果や発表論文を紹介してきましたが、以下、2020年以降の生命科学コース所属研究室の主要な論文や総説、受賞などの業績をまとめてみました。
教員を太字、学生（学部生?大学院生：既卒含む）をアンダーラインで表しています。論文タイトル（青字）や解説?プレスリリース（赤字、日本語による解説）をクリックするとそれぞれのリンクに移動することができます。

<研究論文等>

2025年
Saitoh Y, Takeda K, Okawachi K, Tanimura Y. (2025) High dose of ascorbic acid induces selective cell growth inhibition and cell death in human gastric signet-ring cell carcinoma-derived NUGC-4 cells. Biochim Biophys Acta Gen Subj. 1869(2):130738.


2024年
Fukunaga K, Abe A, Ito K, Oikawa K, Tsuji M, Kawase M. (2024) Latitudinal adaptation and dispersal pathway suggested by geographical distribution of transposable elements inserted in the SiPRR37 gene in foxtail millet. Genes and Genetic Systems 99:Article ID 24-00023解説

菅裕、阿形清和 他 単細胞ホロゾア?多細胞体制の起源　月刊 細胞 2024年5月号 解説

Aoshima H, Mizuno R, Iwatsu Y, Onishi S, Hyodo S, Ibuki R, Kawagishi H, Saitoh Y. (2024) Inhibitory effect of 2-Aza-8-oxohypoxanthine on tyrosinase activity and melanin production. Cosmetics 11(2): 43. 解説

Okamoto A, Nakanishi T, Tonai S, Shimada M, Yamashita Y (2024) Neurotensin induces sustainable activation of the ErbB-ERK1/2 pathway, which is required for developmental competence of oocytes in mice. Reprod Med Biol. 23(1):e12571 解説

Fukunaga K and Kawase M (2024) Crop Evolution of Foxtail Millet. Plants 13:218. https://doi.org/10.3390/plants130202 解説


2023年
Kondo Y, Ogawa T, Kanno E, Hirono M, Kato-Minoura T, Kamiya R, Yagi T (2023) IC2 participates in the cooperative activation of outer arm dynein densely attached to microtubules. Cell Struct Funct. 48(2):175-185. 解説

Tonai S, Nakanishi T, Yamaoka M, Okamoto A, Shimada M, Yamashita Y (2023) Pre-culture with transferrin-Fe3+ before in vitro maturation improves the developmental competence of porcine oocytes matured in vitro. Reprod Med Biol. 22(1):e12529 解説

福永健二 (2023)　アワの遺伝学　雑穀研究 38, 10-17 解説

Yagi T, Toda A, Ichikawa M, Kurisu G (2023) Regulation of motor activity of ciliary outer-arm dynein by the light chain 1; Implications from the structure of the light chain bound to the microtubule-binding domain of the heavy chain. Biophysics and Physicobiology 解説

齋藤靖和 (2023) 細胞老化に伴う特徴的な変化からみるSenolysis/Senostaticsの可能性 月刊 細胞 Vol. 55(2), 32-35 解説

Yamamoto N, Takeuchi H, Yamaoka M, Nakanishi T, Tonai S, Nishimura R, Morita T, Nagano M, Kameda S, Genda K, Kawase J, Yamashita Y (2023) Lipopolysaccharide (LPS) suppresses follicle development marker expression and enhances cytokine expressions, which results in fail to granulosa cell proliferation in developing follicle in cows.Reprod Biol. 23(1): 100710 解説


2022年
Suzuki H, Watanabe H, Abe Y (2022) Assisted reproductive techniques for canines: preservation of genetic material in domestic dogs. Journal of reproduction and development 68: 1-11

Saitoh Y, Yonekura N, Matsuoka D, Matsumoto A (2022) Molecular hydrogen suppresses Porphyromonas gingivalis lipopolysaccharide-induced increases in interleukin-1 alpha and interleukin-6 secretion in human gingival cells. Molecular and Cellular Biochemistry 477: 99-104  解説

Fukunaga K, Abe A, Mukainari Y, Komori K, Tanaka K, Fujihara A, Yaegashi H, Kobayashi M, Ito K, Ohsako T & Kawase M (2022) Recombinant inbred lines and next-generation sequencing enable rapid identification of candidate genes involved in morphological and agronomic traits in foxtail millet. Scientific Reports 解説　プレスリリース


2021年
Saitoh Y, Yamaguchi Y, Okada Y (2021) Protective effects of dissolved molecular hydrogen against hydrogen peroxide-, hydroperoxide-, and glyoxal-induced injuries to human skin keratinocytes. Molecular and Cellular Biochemistry. 476:3613-3622  解説

Seino H, Kawaguchi N, Arai Y, Ozawa N, Hamada K, Nagao N (2021) Investigation of partially myristoylated carboxymethyl chitosan, anamphoteric-amphiphilic chitosan derivative, as a new material for cosmetic and dermal application. J. Cosmet. Dermatol. 20, 2332–2340

Nakanishi T, Tanaka R, Tonai S, Lee JY, Yamaoka M, Kawai T, Okamoto A, Shimada M, Yamashita Y (2021) LH induces de novo cholesterol biosynthesis via SREBP activation in granulosa cells during ovulation in female mice. Endocrinology. 162, bqab166 解説

八木俊樹, 藤田洋介, 上村慎治, 岩本裕之 (2021) 温度変化によって生じる鞭毛軸糸の構造変化 Spring8/SACLA 利用成果集(6号)9巻375-379
八木俊樹, 西山雅祥 (2021) 高圧力下で蘇る鞭毛運動『化学』（化学同人）(4号)76巻41-45

八木俊樹, 戸田暁之, 市川宗厳, 栗栖源嗣 (2021) 繊毛ダイニン軽鎖と重鎖微小管結合部位の複合体構造ー見えてきた軽鎖LC1の役割ー生物物理学会誌(1号)61巻20-22

伊原伸治, 佐々木ひかる, 中寺紗希 (2021) モデル生物を用いた分泌タンパク質の凝集?脱凝集機構の解析.  月刊細胞　53: 63-65 解説

Nakanishi T, Okamoto A, Ikeda M, Tate S, Sumita M, Kawamoto R, Tonai S, Lee JY, Shimada M, and Yamashita Y (2021) Cortisol induces follicle regression, while FSH prevents cortisol-induced follicle regression in pigs. Molecular Human Reproduction, gaab038 解説

Ihara S（2021）N-terminally endogenous Mkate2-tagged Him-4 in Caenorhabditis elegans. Micropublication Biology. 10.17912/micropub.biology.000386. 解説

Saitoh Y, Tanaka A, Hyodo S (2021)  Protective effects of　polyvinylpyrrolidone-wrapped fullerene against nitric oxide/peroxynitrite-induced cellular injury in human skin keratinocytes. Journal of　Nanoscience and Nanotechnology 21: 4579–4585 解説

Saitoh Y, Kawasaki N, Eguchi N, Ikeshima M (2021) Combined treatment with dissolved hydrogen molecule and platinum nanocolloid exerts carcinostatic/carcinocidal effects by increasing hydrogen peroxide generation and cell death in the human gastric cancer cell line NUGC-4. Free Radical Research 55: 211-220 解説

Fukunaga K, Matsuyama S, Abe A, Kobayashi M, Ito K（2021）Insertion of a transposable element in Less Shattering1 (SvLes1) gene is not always involved in foxtail millet domestication.　?Genetic Resources and Crop Evolution 68: 2923–2930 解説


2020年
福永健二, 大迫敬義 (2020) モデル植物となったエノコログサ―その雑草生物学への適用. 雑草研究65:140-149 解説

Tonai S, Kawabata A, Nakanishi T, Lee JY, Okamoto A, Shimada M, Yamashita Y (2020)　Iron deficiency induces female infertile in order to failure of follicular development in mice.  Journal of Reproduction and Development 66: 475-483 解説

Abe Y, Asano T, Wakasa I, Kume A, Yokozawa S, Umemiya‐Shirafuji R, Suzuki H (2020) Cryopreservation of canine spermatozoa using a skim milk‐based extender and a short equilibration time. Reproduction in Domestic Animals 55: 1548–1553

Fukunaga K, Nur MZ, Inoue T, Taketa S, Ichitani K (2020) Phylogenetic analysis of the Si7PPO gene in foxtail millet, Setaria italica, provides further evidence for multiple origins of the negative phenol color reaction phenotype. Genes and Genetic Systems 95: 191-199 解説

Saitoh Y, Umezaki T, Yonekura N, Nakawa A (2020) Resveratrol potentiates intracellular ascorbic acid enrichment through dehydroascorbic acid transport and/or its intracellular reduction in HaCaT cells. Molecular Cellular Biochemistry 467:57-64  解説

Yagi T, Nishiyama M (2020) High hydrostatic pressure induces vigorous flagellar beating in Chlamydomonas non-motile mutants lacking the central apparatus. Scientific Reports 10: 2072  解説